EXPLORNA Science Publications Presentations Members

Marie Curie Excellence Grant

“Study of RNA components by the Synthesis of Small Molecules”

Contract No. MEXT-CT-2006-039149, Dr. Dionisios Vourloumis,

Budget : € 1.619.960, Duration : Feb 2007– Jan 2011

Scientific Publications

• Katsoulis, I.A.; Pyrkotis, C.; Papakyriakou, A.; Kythreoti, G.; Zografos, A.L.; Mavridis, I.; Nahmias, V.R.; Anastasopoulou, P.; Vourloumis, D., “Unnatural rigid scaffolds targeting the bacterial ribosome”, ChemBioChem 2009, 10, 1969-1972
• Stathakis, C.I; Mavridis, I.; Kythreoti, G.; Papakyriakou, A.; Katsoulis, I.A.; Cottin, T.; Anastasopoulou, P.; Vourloumis, D., “Second generation analogues of rigid 6,7-spiro scaffolds targeting the bacterial ribosome”, Bioorg. Med. Chem. Lett. 2010, 20, 7488-7492
• Cottin, T.; Pyrkotis, C.; Stathakis, C.I; Mavridis, I.; Katsoulis, I.A.; Anastasopoulou, P.; Kythreoti, G.; Zografos, A.L.; Nahmias, V.R.; Papakyriakou, A.; Vourloumis, D., “Designed spiro-bicyclic analogues targeting the ribosomal decoding center”, ChemBioChem 2011, 12, 71-87
• Kythreoti, G.; Vourloumis, D., “A Homo sapiens Cytoplasmic Ribosomal Decoding A-site Affinity Screen Evaluating Aminoglycoside- and Analogues-Binding”, Anal. Biochem. 2011, 412, 102-107
• Katsoulis, I. A.; Kythreoti, G.; Papakyriakou, A.; Koltsida, K.; Anastasopoulou, P.; Stathakis, C. I; Mavridis, I.; Cottin, T.; Saridakis, E.; Vourloumis, D., “Synthesis of 5,6-spiroethers and evaluation of their affinity for the bacterial A-site”, ChemBioChem 2011, 12, 1188-1192

Conferences

• Dionisios Vourloumis et al. “Chemical Biology of Small Molecules Interfering with Protein-Synthesis” ESF-COST High-Level Research Conference: Natural Products Chemistry, speaker and session chair, Biology and Medicine, Acquafredda di Maratea, Italy, May 18–23, 2008. Book of Abstracts 2008, pages 60–61.
• Anastasopoulou Panoula, Zografos Alexandros L., Katsoulis Ioannis, Athanasios Papakyriakou, Kythreoti Georgia, Mavridis Ioannis, Vourloumis Dionisios* “Chemical Biology of Small Molecules Interfering with Protein-Synthesis”, BOSS XI, 11^th Belgian Organic Synthesis Symposium, Ghent, Belgium, July 13 - 18, 2008. Book of Abstracts 2008, P26.
• Kythreoti Georgia, Zografos Alexandros L., Katsoulis Ioannis, Athanasios Papakyriakou, Anastasopoulou Panoula, Mavridis Ioannis, Vourloumis Dionisios* “Chemical Biology of Small Molecules Interfering with Protein-Synthesis”, XXth International Symposium on Medicinal Chemistry, Vienna, Austria, August 31 - September 4, 2008. Abstract published in Drugs of the Future 2008, 33, Suppl. A, P249.
• Dionisios Vourloumis et al. “Chemical Biology of Novel Ridgid Scaffolds with Antibiotic Potential” 10^th International Conference in Medicinal Chemistry: Drug discovery and design, University of Patra, Greece, March 18–20, 2009, book of abstracts, P26.
• Pyrkotis, C.; Katsoulis, I.A.; Papakyriakou, A.; Kythreoti, G.; Zografos, A.L.; Mavridis, I.; Nahmias, V.R.; Anastasopoulou, P.; Vourloumis, D., “Unnatural rigid scaffolds targeting the bacterial ribosome”, 10^th Tetrahedron Symposium, “Challenges in Organic and Bioorganic Chemistry”, Paris, France, June 23-26, 2009 book of abstracts, C026.
• Mavridis, I.; Anastasopoulou, P.; Katsoulis, I.A.; Pyrkotis, C.; Papakyriakou, A.; Kythreoti, G.; Zografos, A.L.; Nahmias, V.R.; Vourloumis, D., “Chemical Biology of Novel Rigid Scaffolds with Antibiotic Potential”, International Symposium on Advances in Synthetic and Medicinal Chemistry, Kiev, Ukraine, August 23-27, 2009 book of abstracts, page 168, P040.
• Katsoulis, I.A.; Pyrkotis, C.; Papakyriakou, A.; Kythreoti, G.; Cottin, T.; Zografos, A.L.; Mavridis, I.; Nahmias, V.R.; Anastasopoulou, P.; Vourloumis, D., “Novel Spirocyclic Aminocyclitols: Simplified Rigid Structures with Antibiotic Activity”, 3^rd Hellenic Symposium on Organic Synthesis, “From Chemistry to Biology, Medicine and Materials Science”, Athens, Greece, October 15-17, 2009 book of abstracts, L08.
• Anastasopoulou, P.; Nahmias, V.R.; Zografos, A.L.; Pyrkotis, C.; Katsoulis, I.A.; Papakyriakou, A.; Kythreoti, G.; Mavridis, I.; Vourloumis, D., “Novel Orthogonally Functionalized 2-DOS Analogues”, 3^rd Hellenic Symposium on Organic Synthesis, “From Chemistry to Biology, Medicine and Materials Science”, Athens, Greece, October 15-17, 2009 book of abstracts, P03.
• Anastasopoulou, P.; Efthimiadou, E.; Katsarou, M.; Katsoulis, I.A.; Kythreoti, G.; Mavridis, I.; Nahmias, V.R.; Papakyriakou, A.; Pitsinos, E.N.; Pyrkotis, C.; Zografos, A.L.; Vourloumis, D., “Antibiotics, anti-Angiogenics and Diagnostics”, COST CM0804, “Chemical Biology with Natural Products”, Workshop 2009, Certosa di Pontignano, Siena, Italy, December 03-06 2009, book of abstracts, O23.
• Ioannis A. Katsoulis, Dionisios Vourloumis, Athanasios Papakyriakou, Constantina Pyrkotis, Thomas Cottin, Christos I. Stathakis, Georgia Kythreoti, Panoula Anastasopoulou, Ioannis Mavridis, “Synthesis of spiro-aminocyclitol analogs and their interaction with the ribosomal RNA”, ACS National Meeting; March 21-25, 2010, San Francisco USA, ORGN-286. Also selected and presented in the SCIFI-mix of the same conference.
• Anastasopoulou, P.; Cottin, T.; Katsoulis, I.A.; Koltsida, K.; Kythreoti, G.; Mavridis, I.; Nahmias, V.R.; Papakyriakou, A.; Pyrkotis, C.; Zografos, A.L.; Vourloumis, D., “Targeting RNA with small molecules”, COST CM0804, “Natural Products as Drugs and Leads for Drugs”, Workshop 2010, Orthodox Academy of Crete, Kolymvari, Crete, Greece, October 12-15 2010, book of abstracts, pages 37-38.